MARIOS DIMOPOULOS, CLINICAL NUTRITIONIST, FELLOW OF THE AMERICAN COUNCIL OF APPLIED CLINICAL NUTRITION.
BLOG ABOUT NUTRITION AND FOOD SUPPLEMENTS.
NUTRITIONAL MEDICINE AND NATUROPATHY.
Marios Dimopoulos Clinical Nutritionist, Author, Fellow of the American Council of the Applied Clinical Nutrition
Παρασκευή, 9 Μαΐου 2014
Life Extension Foundation: It's great work about the prevention and treat of diseases with food supplements
Circumvent Today’s Leading Cause of Death
By William Faloon
John Snow, MD, is the genius who created the modern science of epidemiology.1
Dr. Snow demonstrated that feces-laden water consumed by the people of London in the mid-1800s was causing cholera and other epidemic diseases.1
Dr. Snow had no idea that microscopic bacteria were behind cholera. Doctors at that time had not yet recognized the “germ theory” of disease. He nonetheless concluded that contaminated water was the source of a self-replicating poison that was killing thousands of London residents.
Few people of the day followed Dr. Snow’s admonition to boil drinking water and avoid fluids that emanated from the bowels of cholera patients.
It might not surprise you that the medical establishment did not agree with Dr. Snow. Physicians in 1854 attributed cholera and other enteric diseases to the foul smelling gasses produced by piles of rotting garbage and raw sewage that characterized London at that time.1
Rational decision making by the medical establishment has not improved much on a relative basis since Dr. Snow’s time.
Mainstream medicine continues to overlook proven methods to prevent, mitigate, or eradicate chronic disorders. The result is that too many Americans needlessly suffer and die.
A fundamental purpose of Life Extensionis to investigate and identify the underlying culprits behind today’s epidemics and devise practical protocols to circumvent them.
Over the past 10 years, Life Extension has accumulated a wealth of new lifesaving knowledge. This article describes the modern world’s leading cause of death. It then reviews the completely revised 2014 edition of Disease Prevention and Treatment, a textbook designed for professionals and the lay public alike.
One of today’s great misconceptions is how people die. Most believe disease is the leading cause of death. Nothing could be further from the truth.
While data is regularly published showing what diseases people die with, missing is what caused the disease to manifest in the first place.
The number one cause of death throughout the world is medical ignorance. Not just the Western world, but the entire world. This fact can be demonstrated by looking at the degree of ignorance in developing countries today.
In parts of Africa, for example, AIDS is not considered to be a viral disease.2 Instead, the belief is that one contracts AIDS by “thinking” they may contract AIDS. Therefore, according to this backward logic, to even “think” that practicing safe sex will prevent AIDS causes one to contract the disease. The result of this fallacy is that HIV infection has spread at epidemic proportions in Africa, as people freely engage in dangerous sex practices and intentionally pretend that there is no such thing as HIV-AIDS.3,4
One reason that new viral diseases keep emanating from China is that sanitary conditions are very bad in many parts of the country. Some rural Chinese farmers live under the same roof as their livestock, increasing the likelihood of transmitting animal viruses to humans. Apartment buildings constructed during the communist regime have such improperly installed plumbing that it is not unusual for the toilet contents of those living upstairs to wind up in their downstairs neighbor’s sinks. Rampant infectious disease involving the same organism has been known to strike virtually everyone living in these decrepit apartment buildings.
More than 1.8 million humans die annually from water-borne bacterial diarrhea includingcholera.5 While many Third World populations have little choice, it’s not the cholera bacterium that is their enemy. The preventable culprit is their ignorance about the dangers of drinkingcontaminated water. 1,5,6
It’s Nearly as Bad in the Western World
Arrogant doctors in the Western world pretend that they have somehow lifted themselves out of the sea of oblivion that caused so many needless deaths in the past.
The unfortunate fact is that medical ignorancein the Western world is also the leading cause of death; it just consumes its victims in other ways. Doctors who would ridicule the stupidity of disease causation in developing nations don’t understand that their own oversight is also easy to criticize.
For example, hospitalized patients continue to die needlessly due to malnutrition even in industrialized countries.7 Despite numerous studies documenting the negative effects of hospitalization on nutritional status, very little is being done to correct this problem. 8-11 The result is that hospitalized Americans continue to perish from malnutrition, just as those in the Third World continue contracting water-borne infections at epidemic proportions—two diseases with the same underlying cause… medical ignorance!
If doctors can’t get it right in hospitals when it comes to something as easy as measuring the calorie intake of patients, then can we really expect them to optimally treat complex disease states? The answer is a resounding no!
In the brand new 2014 edition of the book Disease Prevention and Treatment, you will find out how medical ignorance in the so-called modern world deprives patients of life-saving treatments and contributes to unnecessary suffering and death.
Needless Cancer Deaths
Despite proclamations of progress, cancer continues to inflict an epidemic of disability and death on the aging American population.
When a primary tumor is surgically removed, the body producesgrowth factors to heal the surgical wound. The problem is that these same growth factors also promote the proliferation of cancer cells that may have already spread (metastasized) to other parts of the body.12,13 If drugs that suppressed these growth factors were administeredprior to cancer surgery, many lives could be spared. The sad fact is that most oncologists do not even consider prescribing drugs and nutrients before surgery that not only suppress growth factors, but also markedly reduce the metastatic potential of the primary tumor. In the 2014 edition of Disease Prevention and Treatment, we discuss new approaches to treating cancer both before and after surgery that could result in many more successful long-term outcomes.
Cancer cells are uniquely able to adapt to toxic environments, which is why chemotherapy drugs have such a high failure rate. Researchers have identified survival mechanisms that cancer cells employ to avoid obliteration by chemotherapy drugs and other conventional therapies, yet few practicing oncologists incorporate these synergistic strategies into clinical practice. The 2014 edition of Disease Prevention and Treatment identifies therapies that may complement cancer treatments to improve patient outcomes.
Radiation has been used to kill cancer cells for over 100 years, but doctors continue to overlook novel methods to enable this therapy to better treat the disease. The 2014 edition of Disease Prevention and Treatment contains voluminous data on how cancer patients may achieve better results when having to undergo radiation therapy.
Don’t Let Viruses Get You
Each year, tens of millions of Americans suffer acute viral outbreaks that result in debilitating cold-flu sicknesses, herpes, and shingles recurrences, and lethal episodes of influenza.
While effective therapies exist to combat these diseases, the delay in initiating treatment too often results in failure to contain the virus. The 2014 edition of Disease Prevention and Treatmentidentifies novel drug-nutrient-hormone cocktails that can quickly suppress or destroy a broad array of common viruses.
The most important recommendation, however, is to encourage patients to initiate these comprehensive therapies at the very first symptom of a viral infection. Few doctors understand that treatment delay past 48 hours renders even the most advanced anti-viral approaches virtually useless.
Victims of HIV and hepatitis know how difficult it is to kill a virus once it gains a foothold inside the cells of the body. For those afflicted with chronic viral infections, the 2014 edition of Disease Prevention and Treatmentprovides a plethora of immune-boosting strategies designed to contain difficult-to-manage viruses.
Control High Blood Pressure
High blood pressure is a silent epidemic that threatens the lives of one in every three American adults.14 Of those taking blood pressure medications, optimal control rates are typically less than half.14,15 This means that the majority of those diagnosed with hypertension spend most of their day with blood pressure levels that are dangerously elevated.
Since increased blood pressure is a major risk factor for heart disease, stroke, congestive heart failure, and kidney disease, it acts as an accomplice in millions of deaths each year.16
Mainstream medicine has fallen fatally short of relieving high blood pressure. A major problem is that conventional medicine’s definition of what constitutes acceptable blood pressure levels is far too high. In the 2014 edition of Disease Prevention & Treatment, readers will learn about a dangerous assumption made by doctors regarding anti-hypertensive drugs, optimal blood pressure targets, and ways to better manage blood pressure.
Avoid the Dangers of Chronic Stress
Chronic and unremitting stress can increase our risk of suffering from a barrage of anxiety- and pressure-related diseases ranging from high blood pressure to dementia to depression.
Regrettably, while chronic stress produces significant adverse health effects, conventional medicine often relies upon psychoactive drugs to mask stressed patients’ symptoms. At the same time, mainstream stress management strategies often fail to address biochemical abnormalities, such as imbalanced adrenal hormone levels, that contribute to the detrimental health effects of chronic stress.17-19
At the core of chronic stress is deregulation of the hypothalamic-pituitary-adrenal (HPA) axis, an interconnected network of physiologic command terminals that governs the production of stress hormones like cortisol, epinephrine, and norepinephrine. Chronic stress leads to desynchronization of the HPA axis and subsequent imbalances in stress hormone levels, a critical feature of stress-related illness.
The 2014 edition of Disease Prevention and Treatment describes the dangers of chronic stress, how it contributes to various diseases, and how one can optimize their stress response by combining healthy lifestyle habits with scientifically studied natural therapies.
Overlooked Multiple Sclerosis Therapy
More than three decades ago a natural intervention was hypothesized to be an environmental determinant of multiple sclerosis incidence.20,21
Since then, numerous scientific studies have shown that this common natural compound can dramatically modulate the cascade of autoimmunity and inflammation that claims the lives of so many multiple sclerosis patients.22,23 Moreover, evidence shows many multiple sclerosis patients have very low levels of the natural substance in their blood.24
Despite robust findings suggesting this inexpensive natural therapy should be an integral part of every multiple sclerosis patient’s treatment plan, conventional medicine still fails to recommend it. In the 2014 edition of Disease Prevention and Treatment, you will learn about this underappreciated multiple sclerosis therapy as well as a multitude of other innovative disease treatments that conventional medicine continues to overlook.
Keeping the Blood Flowing
Atherosclerosis is the most deadly disease in the United States, yet most doctors still do not understand how it develops. While most people think of their arteries becoming clogged like a pipe, the fact is that the aging process damages the inner linings of blood vessels, even when conventional risk factors such as cholesterol and blood pressure are within normal ranges.25
While high cholesterol levels contribute to atherosclerosis, the mechanism by which it most damages the arterial wall is quite different than what drug companies promote. When levels of cholesterol (and other atherogenic risk factors) are too high, there is a corresponding reduction in the amount of nitric oxide available to the endothelial lining of the arteries.26
Nitric oxide is a critically needed substance that enables the arteries to expand and relax with youthful elasticity.27 The encouraging news is that novel approaches are available that have been shown to safely increase nitric oxide and reverse atherosclerosis markers in humans and animals.28-33
In the 2014 edition of Disease Prevention and Treatment, readers will learn how to circumvent the many overlooked factors that make aging humans so vulnerable to artery disease and subsequent stroke and heart attack.
Protect Healthy Tissues Against Lethal Radiation Damage
Even if cancer is completely cured by radiation therapy, there is sometimes severe peripheral damage to healthy tissues known as radiation fibrosis.34 Life Extension long ago advised those undergoing radiation to use a drug-nutrient combination that was shown to promote healing time and reduce pain following radiation damage.
A more dangerous form of radiation damage, however, occurs when treating cancers involving the brain. The high levels of radiation used to treat tumors in the brain can result in a lethal side effect called radiation necrosis that manifests long after the therapy is discontinued.35-37
The swelling of the brain caused by radiation necrosis can lead to dementia or death.38,39 Doctors treat the brain swelling by administering anti-inflammatory steroid drugs. At some point, steroid drug therapy fails. Years ago, one expert complained that no matter how many brain tumors are cured with radiation therapy, the patients eventually died from radiation necrosis.
What conventional doctors overlook is that even when brain swelling is temporarily controlled, the radiation necrosis process itself continues to stimulate inflammatory cytokines. The result is a vicious cycle where damaged brain tissues keep provoking inflammatory cytokines that cause even more necrotic damage, which then promotes even more inflammatory cytokine production (and more necrotic damage).
In the 2014 edition of Disease Prevention and Treatment, a breakthrough drug-nutrient cocktail is introduced to suppress the chronic inflammatory-cytokine cascade and gain long-term control over radiation necrosis.
Why You’ll Want This Book in Your Library or on Your Coffee Table
For the past 33 years, Life Extension has published life-saving information a decade or more ahead of conventional medicine. A case-in-point is Life Extension’s advice to take low-dose aspirinto prevent heart attacks. While mainstream hospitals like Johns Hopkins now advocate aspirin to prevent heart attacks, the Life Extension Foundation® published evidence about aspirin’s benefits back in 1983. The Life Extension Foundation® then spent 15 years battling the FDA to force the agency to recognize the cardio-protective effects of low-dose aspirin.
When a serious medical disorder develops, most people have no one to turn to other than their doctor. The problem is that physicians are often too busy to keep up with the latest research findings. As a result, many patients suffer and die even though advanced therapies already exist that could cure them.
For example, in 2005 “Tamiflu®” became a household word as fears of an avian flu epidemic caused a shortage of this anti-viral drug. Those who purchased the year 2003 edition of Disease Prevention and Treatment, however, learned about Tamiflu before the public and were advised about the benefits of having it available to prevent a flu virus infection.
A stark illustration of the failure of doctors to recognize the value of life-saving medical breakthroughs was a study showing that the drug cimetidine improved survival odds in a group of colon cancer patients.40 In this landmark study, patients with an aggressive form of colon cancer took 800 mg of cimetidine for one year after surgery. After ten years, there was nearly a60% improvement in survival in the group that took cimetidine.
As early as 1985, the Life Extension Foundation recommended cimetidine as an adjuvant cancer therapy. If you had been a Life Extension member and contracted colon cancer, your odds of dying could have been reduced dramatically.
Many colon cancer patients learned about the enormous value of cimetidine in the year 2003 edition ofDisease Prevention and Treatment. The brand new 2014 edition of Disease Prevention and Treatment provides even more novel therapies for colon cancer patients to consider.
For those afflicted with chronic illnesses, the new information contained in the 2014 edition ofDisease Prevention and Treatmentcould result in a liberating experience. When a medical concern arises, you don’t want to be left in the darkness of scientific ignorance.
By keeping the latest edition of Disease Prevention and Treatment close by, you will quickly be able to use the expanded index to educate yourself about novel therapies that have shown efficacy in peer-reviewed studies, but have not yet made it into conventional medical practice.
Save Over 60% on Disease Prevention and Treatment
Life Extension has spent millions of dollars in researching, writing, and editing the 130 chapters that comprise the 2014 edition ofDisease Prevention and Treatment. We expect to recoup some of this expenditure when we release it to book stores in January 2014.
We want every one of our members to have this updated reference book in their homes today. To encourage this, we are offering the book to members at a 64% discount off the cover price of Disease Prevention and Treatmentuntil January 31, 2014.
This beautiful hardbound book retails for $69.95…a far lower price than what medical textbooks like this normally cost. Until January 31, 2014, you can obtain the 2014 edition of Disease Prevention and Treatment for only $24.95.
To order your personal copy of the new Disease Prevention and Treatment reference book, call1-800-544-4440 today.
If you have any questions on the scientific content of this article, please call a Life Extension®Health Advisor at 1-866-864-3027.
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Michalek RD, Rathmell JC. The metabolic life and times of a T-cell. Immunol Rev. 2010 Jul;236:190-202.
Fritz V, Fajas L. Metabolism and proliferation share common regulatory pathways in cancer cells. Oncogene. 2010 Aug 5;29(31):4369-77.
Lloyd-Jones et al. Heart disease and stroke statistics—2010 Update. Circulation. 2010 Feb 23;121(7):e46-e215.
Lloyd-jones et al. Hypertension in adults across the age spectrum. JAMA. 2005 Jul 27;294(4):466-72.
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Jeckel CM, Lopes RP, Berleze MC, et al. Neuroendocrine and immunological correlates of chronic stress in ‘strictly healthy’ populations. Neuroimmunomodulation. 2010;17(1):9-18
Wolkowitz OM, Reus VI, Keebler A, et al. Double-blind treatment of major depression with dehydroepiandosterone. Am J Psychiatry. 1999 Apr;156(4):646-9.
Wolkowitz OM, Reus VI, Manfredi F, et al. Dehydroepiandrosterone (DHEA) treatment of depression. Biol Psychiatry. 1997 Feb 1;41(3):311-8.
Craelius W. comparative epidemiology of multiple sclerosis and dental caries. J Epidemiol Community Health. 1978 Sep;32(3):155-65.
Goldberg P. Multiple Sclerosis: vitamin D and calcium as environmental determinants of prevalence (a viewpoint). Part 1: sunlight, dietary factors and epidemiology. Intern J Environ Stud. 1974, 6: 19-27.
Burton JM, Kimball S, Vieth R, et al. A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis. Neurology. 2010 Jun 8;74(23):1852-9.
Adorini L, Penna G. Control of autoimmune diseases by the vitamin D endocrine system.Nat Clin Pract Rheumatol. 2008 Aug;4(8):404-12.
Soilu-Hänninen M, Laaksonen M, Laitinen I, Erälinna JP, Lilius EM, Mononen I. A longitudinal study of serum 25-hydroxyvitamin D and intact parathyroid hormone levels indicate the importance of vitamin D and calcium homeostasis regulation in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2008 Feb;79(2):152-7.
Gattullo D, Pagliaro P, Marsh NA, Losano G. New insights into nitric oxide and coronary circulation. Life Sci. 1999;65(21):2167-74.
Sugawara J, Komine H, Hayashi K, et al. Effect of systemic nitric oxide synthase inhibition on arterial stiffness in humans. Hypertens Res. 2007 May;30(5):411-5.
Cloarec M, Caillard P, Provost JC, Dever JM, Elbeze Y, Zamaria N. GliSODin, a vegetal sod with gliadin, as preventative agent vs. atherosclerosis, as confirmed with carotid ultrasound-B imaging. Allerg Immunol.(Paris). 2007 Feb;39(2):45-50.
de Nigris F, Williams-Ignarro S, Lerman LO, et al. Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress. Proc Natl Acad Sci USA. 2005 Mar 29;102(13):4896-901.
Sies H, Schewe T, Heiss C, et al. Cocoa polyphenols and inflammatory mediators. Am J Clin Nutr. 2005a Jan;81(1 Suppl):304S-312S.
Grassi D, Lippi C, Necozione S, Desideri G, Ferri C. Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons. Am J Clin Nutr. 2005 Mar;81(3):611-4.
Aviram M, Rosenblat M, Gaitini D, et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr. 2004 Jun;23(3):423-33.
Kaplan M, Hayek T, Raz A, et al. Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J Nutr. 2001 Aug;131(8):2082-9.
Burger A, Löffler H, Bamberg M, Rodemann HP. Molecular and cellular basis of radiation fibrosis. Int J Radiat Biol. 1998 73(4):401-8.
Plimpton SR, Stence N, Hemenway M, Hankinson TC, Foreman N, Liu AK. Cerebral Radiation Necrosis in Pediatric Patients. Pediatr Hematol Oncol. 2013 May 7. [Epub ahead of print]
DeAngelis LM, Delattre JY, Posner JB. Radiation-induced dementia in patients cured of brain metastases. Neurology. 1989 Jun;39(6):789-96.
Crossen JR, Garwood D, Glatstein E, Neuwelt EA. Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy. J Clin Oncol. 1994 Mar;12(3):627-42.
Johannesen TB, Lien HH, Hole KH, Lote K. Radiological and clinical assessment of long-term brain tumour survivors after radiotherapy. Radiother Oncol. 2003 Nov;69(2):169-76.
Matsumoto S, Imaeda Y, Umemoto S, Kobayashi K, Suzuki H, Okamoto T. Cimetidine increases survival of colorectal cancer patients with high levels of sialyl Lewis-X and sialyl Lewis-A epitope expression on tumour cells. Br J Cancer. 2002 Jan 21;86(2):161-7.