The study outlines how excessive alcohol
consumption results in neuro-degeneration as well as behavioral and
cognitive impairments that are hypothesized to contribute to the chronic
and relapsing nature of alcoholism. As a result they aimed to study the
transdermal delivery of cannabidiol (CBD) for the treatment of
alcohol-induced neuro-degeneration. At the conclusion of the study,
results demonstrated the feasibility of using CBD transdermal delivery
systems for the treatment of alcohol-induced neurodegeneration.(1)
Just like THC, CBD is another chemical
found in marijuana, the difference is that it doesn’t get you ‘high.’
Both chemicals are strong antioxidants.
These results justify further preclinical development of transdermal CBD for the treatment of alcohol-induced neurodegeneration. It has been suggested that the neuroprotective effects of CBD observed during binge alcohol induced neurodegeneration are due to its high antioxidant capacity. (1)
The authors note that CBD acts as a
stronger antioxidant than many well-known antioxidants. This new study
was done on rat models, using both a skin patch and regular needle
injection. Both methods produced similar magnitudes of neuroprotection,
approximately 50 percent. Further studies need to be done here before
human trials can begin. It’s surprising that human trials have yet to
begin, it seems they should have began ages ago. Year after year we have
credible published studies showing the clear link between cannabis and a
healthy body environment.
The potential health benefits of
cannabis are overwhelming, and potentially very threatening to the
pharmaceutical industry. It is a shame that despite all of the evidence
supporting the medicinal properties of this plant, it still has a
negative connotation within the mainstream. Nobody can deny it’s
medicinal benefits, and given the tremendous amount of information and
research to support it, it seems pretty clear that this plant is a
natural miracle.
Things seem to be changing, however.
Last week, a European based pharmaceutical company called GW
pharmaceuticals announced that they are set to commence its first ever
phase of clinical trials for the treatment of brain cancer. You can read
more about that here.
A couple of months ago, I wrote an article presenting 20 medical
studies that prove cannabis can cure cancer; I’ve presented them in this
article (see below). If we want to stay on the topic of brain damage,
dozens of studies have shown the potential benefits of cannabis on
damaged brain tissue. A study published in the Journal of Clinical Investigation revealed that cannabinoids promote embryonic and adult hippocampus neurogenesis. (2) The
list goes on and on, and it seems to be never-ending, especially when
it comes to cannabis and the brain. If you would like to know more
there is plenty of information that’s readily available.
Contrary to popular belief, smoking
the Cannabis is not the most effective way in treating disease within
the body as therapeutic levels cannot be reached through smoking.
Creating oil from the plant or eating the plant is the best way to go
about getting the necessary ingredients which are the Cannabinoids.
Also, when Cannabis is heated and burnt it changes the chemical
structure and acidity of the THC. This changes its ability to be
therapeutic and anytime you burn something and inhale it, you create
oxidation within the body which aids in free-radical production.
Humanity does not need to wait for a
pharmaceutical company, or the medical industry to ‘OK’ its use for
medicinal purposes. We constantly look towards these corporations for
methods, approval and availability. This is something we can take into
our own hands, the information is out there and if it’s something you
feel can be of benefit you are free to try it. For medicinal use, it
should be non-GMO, grown without pesticides and completely natural. In
the hands of a pharmaceutical company, or future pill form, it might be
hard to trust.
Below are links to more studies with regards to cancer and cannabis. (20 out of many more)
Brain Cancer
1. A study published in the British Journal of Cancer, conducted
by the Department of Biochemistry and Molecular Biology at Complutense
University in Madrid, this study determined that Tetrahydrocannabinol
(THC) and other cannabinoids inhibit tumour growth. They were
responsible for the first clinical study aimed at assessing cannabinoid
antitumoral action. Cannabinoid delivery was safe and was achieved with
zero psychoactive effects. THC was found to decrease tumour cells in two
out of the nine patients.
2. A study published in The Journal of Neuroscience examined
the biochemical events in both acute neuronal damage and in slowly
progressive, neurodegenerative diseases. They conducted a magnetic
resonance imaging study that looked at THC (the main active compound in
marijuana) and found that it reduced neuronal injury in rats. The
results of this study provide evidence that the cannabinoid system can
serve to protect the brain against neurodegeneration.
3. A study published in The Journal of Pharmacology And Experimental Therapeutics already
acknowledged the fact that cannabinoids have been shown to possess
antitumor properties. This study examined the effect of cannabidiol
(CBD, non psychoactive cannabinoid compound) on human glioma cell lines.
The addition of cannabidiol led to a dramatic drop in the viability of
glioma cells. Glioma is the word used to describe brain tumour. The
study concluded that cannabidiol was able to produce a significant
antitumor activity.
4. A study published in the journal Molecular Cancer Therapeutics outlines
how brain tumours are highly resistant to current anticancer
treatments, which makes it crucial to find new therapeutic strategies
aimed at improving the poor prognosis of patients suffering from this
disease. This study also demonstrated the reversal of tumour activity in
Glioblastoma multiforme.
Breast Cancer
5. A study published in the US National Library of Medicine,
conducted by the California Pacific Medical Centre determined that
cannabidiol (CBD) inhibits human breast cancer cell proliferation and
invasion. They also demonstrated that CBD significantly reduces tumour
mass.
6. A study published in The Journal of Pharmacology and Experimental Therapeutics determined
that THC as well as cannabidiol dramatically reduced breast cancer cell
growth. They confirmed the potency and effectiveness of these
compounds.
7. A study published in the Journal Molecular Cancer showed
that THC reduced tumour growth and tumour numbers. They determined that
cannabinoids inhibit cancer cell proliferation, induce cancer cell
apoptosis and impair tumour angiogenesis (all good things). This study
provides strong evidence for the use of cannabinoid based therapies for
the management of breast cancer.
8. A study published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS) determined that cannabinoids inhibit human breast cancer cell proliferation.
Lung Cancer
9. A study published in the journal Oncogene, by
Harvard Medical Schools Experimental Medicine Department determined
that THC inhibits epithelial growth factor induced lung cancer cell
migration and more. They go on to state that THC should be explored as
novel therapeutic molecules in controlling the growth and metastasis of
certain lung cancers.
10. A study published by the US National Library of Medicine by
the Institute of Toxicology and Pharmacology, from the Department of
General Surgery in Germany determined that cannabinoids inhibit cancer
cell invasion. Effects were confirmed in primary tumour cells from a
lung cancer patient. Overall, data indicated that cannabinoids decrease
cancer cell invasiveness.
11. A study published by the US National Library of Medicine,
conducted by Harvard Medical School investigated the role of
cannabinoid receptors in lung cancer cells. They determined its
effectiveness and suggested that it should be used for treatment against
lung cancer cells.
Prostate Cancer
12. A study published in the US National Library of Medicine illustrates a decrease in prostatic cancer cells by acting through cannabinoid receptors.
13. A study published in the US National Library of Medicine outlined multiple studies proving the effectiveness of cannabis on prostate cancer.
14. Another study published by the US National Library of Medicine determined
that clinical testing of CBD against prostate carcinoma is a must. That
cannabinoid receptor activation induces prostate carcinoma cell
apoptosis. They determined that cannabidiol significantly inhibited cell
viability.
Blood Cancer
15. A study published in the journal Molecular Pharmacology recently
showed that cannabinoids induce growth inhibition and apoptosis in
matle cell lymphoma. The study was supported by grants from the Swedish
Cancer Society, The Swedish Research Council and the Cancer Society in
Stockholm.
16. A study published in the International Journal of Cancer also
determined and illustrated that cannabinoids exert antiproliferative
and proapoptotic effects in various types of cancer and in mantle cell
lymphoma.
17. A study published in the US National Library of Medicine conducted
by the Department of Pharmacology and Toxicology by Virginia
Commonwealth University determined that cannabinoids induce apoptosis in
leukemia cells.
Oral Cancer
18. A study published by the US National Library of Medicine results show cannabinoids are potent inhibitors of cellular respiration and are toxic to highly malignant oral Tumours.
Liver Cancer
19. A study published by the US National Library of Medicine determined
that that THC reduces the viability of human HCC cell lines (Human
hepatocellular liver carcinoma cell line) and reduced the growth.
Pancreatic Cancer
20. A study published in The American Journal of Cancer determined
that cannabinoid receptors are expressed in human pancreatic tumor cell
lines and tumour biopsies at much higher levels than in normal
pancreatic tissue. Results showed that cannabinoid administration
induced apoptosis. They also reduced the growth of tumour cells, and
inhibited the spreading of pancreatic tumour cells.
Sources:
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